BCB 444/544 - Fall Semester 2005
Introduction to Bioinformatics

Bioinformatics and Computational Biology
Iowa State University

Note
  • This website is for the Fall 2005 version of the course

Description

Broad overview of bioinformatics with a significant problem-solving component, including hands-on practice using computational tools to solve a variety of biological problems.  Topics include:  database searching, sequence alignment, gene prediction, RNA and protein structure prediction, construction of phylogenetic trees, comparative and functional genomics. 
Prerequisite: Math 165 or Stat 401 or equivalent.
Course Materials
Syllabus Syllabus PDF
Syllabus Word
Instructors
David Fernández-Baca, Drena Dobbs
209 Atanasoff Hall 106 Molecular Biology
(515) 294-2168 (515) 294-1112
fernande@cs.iastate.edu ddobbs@iastate.edu
Office hours: Monday 2-3 Office hours: Tuesdays 10-11 or by appt.
Teaching Assistant
Michael Terribilini
106 Molecular Biology
(515) 294-4991
terrible@iastate.edu
Office hours: Tuesday 10-11 and Wednesday 11-12
Time and Place Lecture: MWF 10:00 - 10:50 AM Town 270

Lab: Th 1:10 - 3:00 PM 1340 MBB

Evaluation

BCB 444 BCB 544
Midterm Exams 100 points each 125 points each*
Take Home Assignments 150 points 150 points
Final Exam 150 points 200 points
Total 500 points 800 points

*544 students will be required to answer extra questions on each exam.  These questions will emphasize experimental interpretation and design or concepts related to the journal readings. 

Textbook Bioinformatics: Sequence & Genome Analysis, 2nd edition
David W. Mount, Cold Spring Harbor Press, 2004
ISBN 0879697121
Links
Announcement Archive
  • August 5: Course web page posted.
  • August 17: Updated syllabus posted.
  • August 22: Another updated syllabus posted.
  • August 24: August 24th power point slides posted.
  • August 25: Lab 1 posted.
  • August 26: HTML Version of the syllabus posted with links to lecture slides and labs
  • August 31: Updated version of the PAM matrix slides posted - see August 29th Lecture Slides
  • September 2: Updated version of the BLOSUM matrix slides posted - see August 31st Lecture Slides, the correction is on slide 15
  • September 2: Effective Wednesday, September 7th: We will meet in Town 270 for lecture
  • September 7: Office hours posted
  • September 12: Bayesian evolutionary distance slides posted - see September 12th Lecture Slides
  • September 13: Frequently Asked Questions page has been posted
  • September 14: Multiple sequence alignment slides posted - see September 14th Lecture Slides
  • September 14: Two papers posted as required reading for 544 students
  • September 15: Study Guide for Exam 1 posted
  • September 16: Profile slides posted - see September 16th Lecture Slides
  • September 19: Answer keys for Lab 2 and Lab 3 posted
  • September 19: Hidden Markov Model slides posted - see September 19th Lecture Slides
  • September 21: The lectures on Monday, September 26th and Wednesday, September 28th will be in the computer lab in 1340 MBB
  • October 20: Two papers are posted as required reading for BCB544 students in preparation for Exam 2
  • October 21: A study guide for Exam 2 (which is on Friday, October 28) has been posted.
  • October 23: A revised version of Lab 9 has been posted. The revisions were also sent via email.
  • Nov 14:   Another required readiing assignment for 544 has been posted
  • Nov 11:   A required reading assignment for 544 has been posted
  • Nov 28:   Project Guidelines and Presentation schedule posted
  • Dec 5:     All BCB 444 & 544 students required to attend Project Presentations & submit evaluations
  • Dec 6:     Study Guide for Final Exam has been posted
  • Dec 13: The final exam will be on Thursday from 9:45 - 11:45 in Town 270
  • Dec 14: The revised study guide has been posted


Last modified on 9/25/06 MJT

www.cs.iastate.edu/~cs544